NUPTEC Inc. Ltd.

Product Details

Professional Manufaturer of Resins for Protein Purification

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Recombinant Human Keratinocyte Growth Factor 2
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  • Recombinant Human Keratinocyte Growth Factor 2

Catalog No:

NRPA23S

Product Name:

Recombinant Human Keratinocyte Growth Factor 2


Keratinocyte growth factor 2(Keratinocyte Growth Fatcor-2, KGF-2), also known as fibroblast growth factor 10(Fibroblast Growth Factor 10, FGF-10), can bind with heparin and belongs to a member of the FGF superfamily. It mainly acts on the receptor FGFR-2b on the surface of epithelial cell membrane and promotes the phosphorylation of the C- terminal tyrosine residue in the receptor cell. The phosphorylated receptor has tyrosine protein kinase activity, and interact with a series of target proteins in the cell, trigger a signal cascade reaction, play a biological role. Therefore, KGF-2 can specifically promote the growth, proliferation and differentiation of epithelial cells. Compared with other growth factors, it has a more significant role in promoting healing and reducing scar in the repair and regeneration of burns, ulcers and external wounds. Recombinant human keratinocyte growth factor 2(rh-KGF-2) was expressed in E. coli using genetic engineering methods and was consistent with the amino acid sequence in humans.

Product features and technical indicators

Product Name

Recombinant Human Keratinocyte Growth Factor 2(Recombinant Human Keratinocyte Growth Fatcor-2; rh-KGF-2)

Catalog No.

NRPA23

Specifications

100 μg,1mg,10mg,100mg

Product form

Lyophilized powder, 20 mM PB(pH 7.4) before lyophilization

molecular weight

19.2kDa

isoelectric point

9.94
absorption coefficient UV absorption method, extinction coefficient E(0.1% at 280nm)= 1.28

Source

Escherichia coli

Purity

≥ 95%(SDS-PAGE detection)

endotoxin

<50 EU/mg

Save condition

-20 ℃ preservation
Conditions of transport Cold transport of ice packs or dry ice

Validity Period

3 years

activity

EC50:< 100 ng/ml