
Product Details
Professional Manufaturer of Resins for Protein Purification

Catalog No:
NRPA23S
Product Name:
Recombinant Human Keratinocyte Growth Factor 2
Keratinocyte growth factor 2(Keratinocyte Growth Fatcor-2, KGF-2), also known as fibroblast growth factor 10(Fibroblast Growth Factor 10, FGF-10), can bind with heparin and belongs to a member of the FGF superfamily. It mainly acts on the receptor FGFR-2b on the surface of epithelial cell membrane and promotes the phosphorylation of the C- terminal tyrosine residue in the receptor cell. The phosphorylated receptor has tyrosine protein kinase activity, and interact with a series of target proteins in the cell, trigger a signal cascade reaction, play a biological role. Therefore, KGF-2 can specifically promote the growth, proliferation and differentiation of epithelial cells. Compared with other growth factors, it has a more significant role in promoting healing and reducing scar in the repair and regeneration of burns, ulcers and external wounds.
Recombinant human keratinocyte growth factor 2(rh-KGF-2) was expressed in E. coli using genetic engineering methods and was consistent with the amino acid sequence in humans.
Product features and technical indicators
Product Name |
Recombinant Human Keratinocyte Growth Factor 2(Recombinant Human Keratinocyte Growth Fatcor-2; rh-KGF-2) |
Catalog No. |
NRPA23 |
Specifications |
100 μg,1mg,10mg,100mg |
Product form |
Lyophilized powder, 20 mM PB(pH 7.4) before lyophilization |
molecular weight |
19.2kDa |
isoelectric point |
9.94 |
absorption coefficient | UV absorption method, extinction coefficient E(0.1% at 280nm)= 1.28 |
Source |
Escherichia coli |
Purity |
≥ 95%(SDS-PAGE detection) |
endotoxin |
<50 EU/mg |
Save condition |
-20 ℃ preservation |
Conditions of transport | Cold transport of ice packs or dry ice |
Validity Period |
3 years |
activity |
EC50:< 100 ng/ml |
Key words:
Recombinant Human Keratinocyte Growth Factor 2
Classification:
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