NUPTEC Inc. Ltd.

Product Details

Professional Manufaturer of Resins for Protein Purification

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Recombinant human epidermal growth factor
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  • Recombinant human epidermal growth factor

Catalog No:

NRPA11S

Product Name:

Recombinant human epidermal growth factor


Mature human epidermal growth factor (hEGF) is a single-chain low-molecular-weight polypeptide composed of 53 amino acids, with a molecular weight of about 6.2kDa, containing 6 cysteines, forming 3 pairs of disulfide bonds in the chain, stable to acid, alkali and heat, and resistant to degradation by enzymes such as trypsin, chymotrypsin and pepsin. hEGF plays a variety of biological functions by binding to the specific EGF receptor (EGFR) on the cell surface, and can be used in the treatment of surgical trauma, skin ulcer, peptic ulcer, corneal injury, tissue repair and so on. hEGF can automatically combine with EGFR on the cell membrane near the wound, thereby activating protein kinase, accelerating the synthesis of DNA, RNA and protein, promoting and regulating the growth and value-added of epidermal cells, making the wound heal quickly and repairing skin tissue. The recombinant human epidermal growth factor (rh-EGF) is expressed by extracellular secretion, the amino acid sequence and molecular structure are consistent with the natural hEGF, and has complete biological activity.

Product features and technical indicators

Product Name

Recombinant Human Epidermal Growth Factor (Recombinant Human Epidermal Growth Factor, rh-EGF)

Catalog No.

NRPA11

Specifications

1 mg,10mg,100mg

Product form

Lyophilized powder, 5 mM PB(pH 6.8) before lyophilization

molecular weight

6.2 kDa

isoelectric point

4.78
Purity ≥ 95%(SDS-PAGE detection)
absorption coefficient UV absorption method, extinction coefficient E(0.1% at 280nm)= 3.03

Source

Escherichia coli
endotoxin

<50 EU/mg

Save condition

-20 ℃ preservation
Conditions of transport Cold transport of ice packs or dry ice

Validity Period

3 years

activity

Activity ≥ 1*10U/mg(BALB/c 3T3 cell assay)